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Itraconazole for cell activation

Itraconazole for cell activation is available 0 time from Biovision labs

Description A synthetic broad-spectrum triazole antifungal agent with the mode of action being through Inhibition of cytochrome P450 dependent enzymes including 14α-demethylase. Recently, it has been shown that Itraconazole inhibits Hedgehog (Hh) signaling pathway activity (IC50 = 0.8 µM) as well as blocks the VEGFR2 glycosylation, trafficking, and signaling in endothelial cells.
Peptide sequence N/A
CAS number 84625-61-6
Molecular weight 705.63
Category Biochemicals
Other name (2R,4S)-rel-1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one; Oriconazole, R51211, Sporanox
Molecular formula C₃₅H₃₈Cl₂N₈O₄
Physical appearance White solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? No
Purification ≥97%
Reconstitute instructions DMSO
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 60 months
Storage instructions Protect from light and air
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetItraconazole for activation
Short name Itraconazole for activation
Technique activation
Alternative name Itraconazole to measure cellular activation
Tissue cell
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Itraconazole for cell activation -
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • Itraconazole
  • for
  • activation
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