Mouse Monoclonal [clone MEM-E/07] (IgG1) to Human HLA-E Antibody
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Catalog numberGEN246670
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PricePlease ask
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Size50ug
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Also known asHLA-E
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Other namesHLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, alpha chain E; MHC HLA-E alpha-1; lymphocyte antigen; MHC HLA-E alpha-2.1; MHC class I antigen E; HLA class I histocompatibility antigen, E alpha chain; major histocompatibility complex, class I, E; MHC class I antigen E
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameHLA-E
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Gene name synonimsN/A
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Other gene namesHLA-E; HLA-E; MHC; QA1; EA1.2; EA2.1; HLA-6.2; HLA-6.2; HLAE
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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CloneMEM-E/07
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognized native surface-expressed HLA-E, but not denatured heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results revealed that the antibody cross-reacts with some classical MHC Class I molecules (MHC Class Ia): HLA-B7 (strongly), HLA-B8 (moderately), HLA-B27, -B44 (weakly); Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodProtein A Purified
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Form AppearancePBS, 15 mM sodium azide, approx., pH 7.4.
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ConcentrationN/A
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Storage and shippingStore at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
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Tested applicationsImmunohistochemistry (IHC - Paraffin), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolHLA-E, SMC2, SNAR-E, IPCEF1, SNRPE, KLRC3, TLE4, GUCY2EP, IGHV1-69
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Short nameMouse Monoclonal [clone MEM-E/07] (IgG1) HLA-E Antibody
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TechniqueMouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeIgG1
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SpeciesHuman, Humans, Mouses
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Alternative nameAnti-Mouse Monoclonal [clone MEM-E/07] (IgG1) to Human HLA-E
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Alternative techniqueantibodies, murine
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Alternative to gene targetmajor histocompatibility complex, class I, E, EA1.2 and EA2.1 and HLA-6.2 and MHC and QA1, HLA-E and IDBG-125081 and ENSG00000204592 and 3133, peptide antigen binding, Plasma membranes
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Clone nameMEM-E
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Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, E
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GenBank acession
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Locus
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Discovery year1988-05-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namestructural maintenance of chromosomes 2
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Synonyms gene
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Synonyms gene name
- SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
- SMC2 structural maintenance of chromosomes 2-like 1 (yeast)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- Condensin I subunits
- Condensin II subunits
- Structural maintenance of chromosomes proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall NF90 (ILF3) associated RNA E
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Synonyms gene name
- small ILF3/NF90-associated RNA E
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GenBank acession
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Locus
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Discovery year2008-07-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small NF90 (ILF3) associated RNAs
Gene info
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Identity
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Gene
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Long gene nameinteraction protein for cytohesin exchange factors 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2009-02-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nuclear ribonucleoprotein polypeptide E
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Synonyms
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GenBank acession
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Locus
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Discovery year1988-11-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sm spliceosomal proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekiller cell lectin like receptor C3
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Synonyms gene name
- killer cell lectin-like receptor subfamily C, member 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-01-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-type lectin domain containing
- Killer cell lectin like receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTLE family member 4, transcriptional corepressor
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Synonyms gene name
- transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
- transducin like enhancer of split 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-12-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- TLE family
- Wnt enhanceosome complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameguanylate cyclase 2E, pseudogene
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Synonyms gene
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Synonyms gene name
- guanylate cyclase 2E
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Synonyms
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Locus
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Discovery year1997-12-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Guanylate cyclase receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 1-69
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Synonyms gene
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
