Recombinant Human DES(1-3) IGF-1

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description

IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

DES 1-3
Gene symbol

DEGS1, DES, YWHAZ, TRR-ACG1-3, TRF-GAA1-3, TRR-CCG1-3, MIR3130-1, TRW-CCA3-3, TRE-CTC1-3, TRP-CGG1-3
Short name

Recombinant DES(1-3) IGF-1
Technique

Recombinant, IGF, igfs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Amoytop Biotech advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens DES(1-3) IGF-1
Alternative technique

rec, igfs

Identity

HGNC:13709
Gene

DEGS1
Long gene name

delta 4-desaturase, sphingolipid 1
Synonyms gene name
- degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
Synonyms
- MLD
- Des-1
- DES1
- FADS7
- DEGS-1
Synonyms name
- sphingolipid delta(4)-desaturase 1
- dihydroceramide desaturase 1
GenBank acession
- AF002668
Locus

1q42.11
Discovery year

2000-11-09
Entrez gene record

8560
Pubmed identfication
- 9188692
- 20105137
Classification
- Fatty acid desaturases
VEGA ID

OTTHUMG00000037496

Identity

HGNC:12855
Gene

YWHAZ
Long gene name

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
Synonyms gene
- YWHAD
Synonyms gene name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Synonyms
- KCIP-1
- 14-3-3-zeta
Synonyms name
- 14-3-3 zeta
- 14-3-3 delta
GenBank acession
- U28964
Locus

8q22.3
Discovery year

1993-09-20
Entrez gene record

7534
Pubmed identfication
- 8617504
- 7890696
RefSeq identity
- NM_145690
Classification
- 14-3-3 phospho-serine/phospho-threonine binding proteins
VEGA ID

OTTHUMG00000134291

Identity

HGNC:34806
Gene

TRR-ACG1-3
Long gene name

tRNA-Arg (anticodon ACG) 1-3
Synonyms gene
- TRNAR21
- TRR-ACG1-1
Synonyms gene name
- transfer RNA arginine 21 (anticodon ACG)
- transfer RNA-Arg (ACG) 1-1
- transfer RNA-Arg (ACG) 1-3
Synonyms
- tRNA-Arg-ACG-1-3
GenBank acession
- HG983594
Locus

14q11.2
Discovery year

2008-08-29
Entrez gene record

100189243
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34984
Gene

TRF-GAA1-3
Long gene name

tRNA-Phe (anticodon GAA) 1-3
Synonyms gene
- TRNAF11
- TRF-GAA1-1
Synonyms gene name
- transfer RNA phenylalanine 11 (anticodon GAA)
- transfer RNA-Phe (GAA) 1-1
- transfer RNA-Phe (GAA) 1-3
Synonyms
- tRNA-Phe-GAA-1-3
GenBank acession
- HG983960
Locus

11q12.1
Discovery year

2008-08-29
Entrez gene record

100189415
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34735
Gene

TRR-CCG1-3
Long gene name

tRNA-Arg (anticodon CCG) 1-3
Synonyms gene
- TRNAR19
- TRR-CCG1-1
Synonyms gene name
- transfer RNA arginine 19 (anticodon CCG)
- transfer RNA-Arg (CCG) 1-1
- transfer RNA-Arg (CCG) 1-3
Synonyms
- tRNA-Arg-CCG-1-3
GenBank acession
- HG983601
Locus

16p13.3
Discovery year

2008-08-29
Entrez gene record

100189173
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34674
Gene

TRW-CCA3-3
Long gene name

tRNA-Trp (anticodon CCA) 3-3
Synonyms gene
- TRNAW3
- TRW-CCA3-1
Synonyms gene name
- transfer RNA tryptophan 3 (anticodon CCA)
- transfer RNA-Trp (CCA) 3-1
- transfer RNA-Trp (CCA) 3-3
Synonyms
- tRNA-Trp-CCA-3-3
GenBank acession
- HG984066
Locus

17p13.1
Discovery year

2008-08-29
Entrez gene record

100189112
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34953
Gene

TRE-CTC1-3
Long gene name

tRNA-Glu (anticodon CTC) 1-3
Synonyms gene
- TRNAE22
Synonyms gene name
- transfer RNA glutamic acid 22 (anticodon CUC)
- transfer RNA-Glu (CTC) 1-3
Synonyms
- tRNA-Glu-CTC-1-3
GenBank acession
- HG983755
Locus

1q23.3
Discovery year

2008-08-29
Entrez gene record

100189385
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34686
Gene

TRP-CGG1-3
Long gene name

tRNA-Pro (anticodon CGG) 1-3
Synonyms gene
- TRNAP8
Synonyms gene name
- transfer RNA proline 8 (anticodon CGG)
- transfer RNA-Pro (CGG) 1-3
Synonyms
- tRNA-Pro-CGG-1-3
GenBank acession
- HG983992
Locus

17p13.1
Discovery year

2008-08-29
Entrez gene record

100189124
Classification
- Cytoplasmic transfer RNAs

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data