TNFRSF10D, CT (TNFRSF10D, DCR2, TRAILR4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor with a truncated death domain, CD264)[TNFRSF10D]
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Catalog numberMBS643987
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PricePlease ask
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SizeNA
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Products_typeAntibody
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ReactivityHuman
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DescriptionThis 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolTNFRSF10D, TNF, TNFRSF1A, TNFRSF1B, LTBR, TNFSF10, TNFRSF10B, CCR6
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Short nameTNFRSF10D, CT (TNFRSF10D, DCR2, TRAILR4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D, Decoy receptor 2, TNF- apoptosis- ligand receptor 4, TRAIL receptor with a truncated death domain, CD264)[TNFRSF10D]
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Techniqueapoptosis, apoptosis pathway
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HostRabbit
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Alternative nametumor necrosis factor receptor superfamily, member 10d, decoy including truncated death domain, CT (tumor necrosis factor receptor superfamily, member 10d, decoy including truncated death domain, DCR2, TRAILR4, TRUNDD, Tumor necrosis factor receptor supergroup member 10D, Decoy receptor 2, tumor necrosis factor-related programmed cellular destruction-inducing ligand receptor 4, TRAIL receptor including a truncated death domain, CD264)[tumor necrosis factor receptor superfamily, member 10d, decoy including truncated death domain]
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Alternative techniquecelldeath
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Alternative to gene targettumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain, CD264 and DCR2 and TRAIL-R4 and TRAILR4 and TRUNDD, TNFRSF10D and IDBG-11632 and ENSG00000173530 and 8793, TRAIL binding, Plasma membranes
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 10d
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 10
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Pubmed identfication
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Classification
- CD molecules
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 10b
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 10b
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine receptor 6
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Synonyms gene
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Synonyms gene name
- chemokine (C-C motif) receptor 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-04-21
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Entrez gene record
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Pubmed identfication
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Classification
- C-C motif chemokine receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data