Human CellExp™ PTPRD, Human Recombinant

  • Catalog number
    P1184-50
  • Price
    Please ask
  • Size
    50 ug
  • Synonyms
    PTPRD, R-PTP-delta
  • Alternative_names
    PTPRD, R-PTP-delta
  • Description
    Enzyme that regulates cell growth, differentiation, mitotic cycle, and oncogenic transformation
  • Recombinant
    Yes
  • Source
    HEK293 cells
  • Purity by SDS PAGE
    > 90%
  • Assay
    SDS-PAGE
  • Endotoxin Level
    < 1.0 EU per/ug
  • Molecular Weight
    140 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
  • Reconstitution Instructions
    Reconstitute in sterile deionized water to the desired protein concentration.
  • Background Information
    Receptor-type tyrosine-protein phosphatase delta is an enzyme that is encoded by the PTPRD gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRD has been shown to interact with PTPRS and liprin-alpha-1. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. Mutations in the PTPRD gene are associated with autism, obsessive–compulsive disorder, and breast cancer.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    PTPRD-DT, PTPRD-AS1, PTPRD
  • Short name
    CellExp™ PTPRD, Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ PTPRD, H. sapiens Rec.
  • Alternative technique
    rec
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    protein tyrosine phosphatase receptor type D
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1992-02-12
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Protein tyrosine phosphatases receptor type
    • Fibronectin type III domain containing
    • I-set domain containing
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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