Active Tumor Necrosis Factor Alpha (TNFa)

Source

NA
Predicted Molecular Mass KD

21.4kDa
Accurate Molecular Mass KD

24kDa
Organism species

Mus musculus (Mouse)
Item Name

Tumor Necrosis Factor Alpha
Alternative Names

DIF; TNF-A; TNFSF2; Cachectin; Tumor Necrosis Factor Ligand Superfamily Member 2
Research Area

Cytokine;Tumor immunity;Infection immunity;
Buffer Formulation

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits

Freeze-dried powder
Isoelectric Point

5
Purity

> 95%
Protein length

Gly57~Leu235
Tag

N-terminal His Tag
Expression System

Eukaryotic expression
Application

Cell culture; Activity Assays.
Manual link
Description

The Active Tumor Necrosis Factor Alpha (TNFa) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

Name

Tumor Stem Cell Assay
Concept

Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data