Glutathione Reductase Antibody (Clone 2B3)

  • Catalog number
    6212-100
  • Price
    Please ask
  • Size
    100 μl
  • Antibody Target
    Glutathione Reductase
  • Target Alternative Name
    GSR, GLUR, GRD1
  • Antibody Type
    Monoclonal
  • Clone
    Clone 2B3
  • Species Reactivities
    Human
  • Immunogen Sequence
    Recombinant human protein purified from E.coli
  • Accession
    P00390
  • Gene Id
    2936
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    1 mg/ml
  • Formulation
    100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol
  • Purification
    Ammonium sulphate precipitation
  • Application
    IP, ELISA.
  • Positive Control
    WB and IP: HeLa cell lysate
  • Application And Usages
    IP: 1-2 µl, ELISA.
  • Description
    Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG). In most eukaryotic cells, GR maintains the ratio of [GSH]/[GSSG] elevated, and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    Glutathione Reductase Antibody (Clone 2B3)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Mouse IgG1
  • Alternative name
    GSH Reductase (antibody to-) (clonality 2B3)
  • Alternative technique
    antibodies
  • Clone name
    2B3
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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