Mitoxantrone

• Catalog number
  1885-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione
• Description
  An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells.
• CAS Number
  65271-80-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₈N₄O₆
• Molecular Weight
  444.48
• Cell Permeable
  No
• Purity
  ≥98%
• Solubilities
  DMSO (~88 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A topoisomerase II inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00242942
• PubChem CID
  4212
• PubChem CID Link
• SMILES
  C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO
• InChi
  InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2
• InChi Key
  KKZJGLLVHKMTCM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Mitoxantrone  
• Short name
  Mitoxantrone
• Alternative name
  Mitoxantrone

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