DIRC2 Antibody, ALEXA FLUOR 488
-
Catalog number
bs-8278R-A488
-
Price
Please ask
-
Size
100ul
-
-
Long name
DIRC2 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
-
Also known as
Anti-DIRC2 PAb ALEXA FLUOR 488
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 488
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
DIRC2
-
Specificity
This is a highly specific antibody against DIRC2.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DIRC2
-
Gene ID Number
84925
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
499nm/519nm
-
Synonyms
Disrupted in renal carcinoma protein 2; DIRC 2; Disrupted in renal cancer protein 2; Disrupted in renal carcinoma 2; FLJ14784; NP_116228; RCC 4; RCC4; Renal cell carcinoma 4; DIRC2_HUMAN.
-
Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-DIRC2 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor
-
French translation
anticorps
-
Gene target
-
Gene symbol
SLC49A4
-
Short name
Anti-DIRC2
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 488
-
Alternative name
DIRC2 Polyclonal Antibody, ALEXA FLUOR 488
-
Alternative technique
antibodies
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
