Recombinant Mouse Tumor Necrosis Factor Receptor Type 2[Tumor Necrosis Factor Receptor Type 2]

• Catalog number
  MBS145573
• Price
  Please ask
• Size
  1 mg

• Products_type
  Recombinant Protein
• Products_gene_name
  [mTNFR2]
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Tumor   Necrosis   Factor   Receptor   2[Tumor   Necrosis   Factor   Receptor  
• Gene symbol
  TNFRSF11A
• Short name
  Recombinant Mouse Tumor Necrosis Factor Receptor 2[Tumor Necrosis Factor Receptor 2]
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse Tumor Necrosis Factor Receptor classification 2[Tumor Necrosis Factor Receptor classification 2]
• Alternative technique
  rec, murine
• Tissue
  tumor

Gene info

• Identity
  HGNC:11908
• Gene
  TNFRSF11A
• Long gene name
  TNF receptor superfamily member 11a
• Synonyms gene
  • PDB2
  • LOH18CR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 11a, activator of NFKB
  • Paget disease of bone 2
  • loss of heterozygosity, 18, chromosomal region 1
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator
• Synonyms
  • RANK
  • CD265
  • FEO
  • ODFR
  • TRANCE-R
• Synonyms name
  • osteoclast differentiation factor receptor
  • receptor activator of nuclear factor kappa B
  • familial expansile osteolysis
  • TRANCE receptor
• GenBank acession
  • AF018253
• Locus
  18q21.33
• Discovery year
  1998-12-04
• Entrez gene record
  8792
• Pubmed identfication
  • 9367155
  • 10615125
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000132779
• Locus Specific Databases
  • LRG_194

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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