Anti-C-SKI/v-SKI (Polyclonal), ALEXA Fluor 594

  • Catalog number
    GENTObs-1684R-A594
  • Price
    Please ask
  • Size
    100 microliters
  • Type
    Conjugated Primary Antibody
  • Conjugated with
    ALEXA FLUOR® 594
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Target Protein Peptide
    C-SKI/v-SKI
  • Specificity
    This antibody reacts specifically with C-SKI/v-SKI
  • Modification
    No modification has been applied to this antibody
  • Modification site
    None
  • Clonality
    Polyclonal Antibody
  • Clone
    Polyclonal Antibodies
  • Concentration
    1ug per 1ul
  • Subcellular locations
    N/A
  • Antigen Source
    KLH conjugated synthetic peptide derived from human C-SKI
  • Gene ID
    6497
  • Swiss Prot
    N/A
  • Applications
    IF(IHC-P)
  • Applications with corresponding dilutions
    IF(IHC-P)(1:50-200)
  • Cross reactive species
    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
  • Cross Reactive Species details
    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information
    SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
  • Purification method
    Purified by Protein A.
  • Storage
    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission
    590nm/617nm
  • Synonyms
    Sloan-kettering viral oncogene homolog; Avian sarcoma viral v ski oncogene homolog; C oncogene; C ski; Ski oncogene; Ski oncoprotein; SKV; v ski avian sarcoma viral oncogene homolog; v ski sarcoma viral oncogene homolog; v-ski sarcoma viral oncogene homolog; SKI_HUMAN.
  • Also known as
    C-SKI/v-SKI Polyclonal Antibody
  • Other name
    Anti-C-SKI/v-SKI Polyclonal
  • Advisory
    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties
    For facs or microscopy Alexa 1 conjugate.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
  • Gene target
  • Gene symbol
    SKI, MBTPS1, HHAT, SMC4, MYB, PCK1, SFTPC, VCX3B, MAF, RFX1
  • Short name
    Anti-C-SKI/v-SKI
  • Technique
    Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    C-SKI/v-SKI Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
  • Alternative technique
    polyclonals, antibodies
  • Alternative to gene target
    v-ski sarcoma viral oncogene homolog (avian), SGS and SKV, SKI and IDBG-86169 and ENSG00000157933 and 6497, repressing transcription factor binding, nuclei, Ski and IDBG-207475 and ENSMUSG00000029050 and 20481, SKI and IDBG-634866 and ENSBTAG00000038716 and 506127
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    structural maintenance of chromosomes 4
  • Synonyms gene
  • Synonyms gene name
    • SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
    • SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-02-22
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Structural maintenance of chromosomes proteins
    • Condensin I subunits
    • Condensin II subunits
    • MicroRNA protein coding host genes
  • VEGA ID
Gene info
  • Identity
  • Gene
    MYB
  • Long gene name
    MYB proto-oncogene, transcription factor
  • Synonyms gene name
    • v-myb avian myeloblastosis viral oncogene homolog
  • Synonyms
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Myb/SANT domain containing
  • VEGA ID
  • Locus Specific Databases
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
    MAF
  • Long gene name
    MAF bZIP transcription factor
  • Synonyms gene name
    • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
  • Synonyms
  • Locus
  • Discovery year
    1991-08-01
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Basic leucine zipper proteins
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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