Recombinant Human Von Hippel-Lindau disease tumor suppressor (VHL)

• Catalog number
  RPC22221-1mg
• Price
  Please ask
• Size
  1mg

• Estimated Turnaround Time
  3-5 weeks
• Gene Name
  VHL
• Alternative Names
  Protein G7; pVHL
• Source
  E.coli
• Purity
  > 85% by SDS-PAGE
• Shipping Conditions
  Ice packs
• Storage conditions
  Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
• Shelf life
  12 months in lyophilized form; 6 months in solution form.
• Restriction
  For research use only. Not for diagnostic procedures.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants
• Description
  Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

• Gene target
  Von   Hippel-Lindau   disease   tumor   suppressor   VHL  
• Gene symbol
  VHL
• Short name
  Recombinant Von Hippel-Lindau disease tumor suppressor (VHL)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Homo sapiens (Human), Humans
• Alternative name
  Rec. H. sapiens Von Hippel-Lindau disease tumor suppressor (von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase)
• Alternative technique
  rec
• Alternative to gene target
  von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase, HRCA1 and pVHL and RCA1 and VHL1, VHL and IDBG-17819 and ENSG00000134086 and 7428, enzyme binding, nuclei, Vhl and IDBG-178105 and ENSMUSG00000033933 and 22346, BT.79817 and IDBG-644624 and ENSBTAG00000016101 and 540957
• Tissue
  tumor

Gene info

• Identity
  HGNC:12687
• Gene
  VHL
• Long gene name
  von Hippel-Lindau tumor suppressor
• Synonyms gene name
  • von Hippel-Lindau syndrome
  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
• Synonyms
  • VHL1
• GenBank acession
  • L15409
• Locus
  3p25.3
• Discovery year
  1986-01-01
• Entrez gene record
  7428
• Pubmed identfication
  • 9671762
• RefSeq identity
  • NM_000551
• VEGA ID
  OTTHUMG00000128668
• Locus Specific Databases
  • UMD Locus Specific Databases
  • LRG_322

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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