(Follicular) Dendritic cells (human) - Clone X-11

Synonym

Accessory B-Cell Macrophages, Complement C9 Neoepitope
StorageTemperature

+5 ± 3 °C
HOST

Mouse
Clone

X-11
Format

Purified, Lyophilized
Species Crossreactivity

human
Application

IHC, FACS
Conjugate

NA
Top Categories

Antibodies
Keywords

Monoclonal; primary antibody
Additonal Description

X-11 detects a neoepitope of the complement component C9 which is expressed when C9 is assembled in the terminal complement complex (TCC). Follicular dendritic cells and sinus lining cells in lymph node and tonsil, and blood dendritic cells express the X-11 antigen. X-11+ blood dendritic cells show typical dendritic veils and are the most potent stimulator cells in an allogenic mixed leukocyte reaction when compared with other leukocytes. X-11+ cells strongly react with anti S100 and weakly with anti CD68. The literature suggests that X-11+ cells are dendritic cells of monocytic origin. Application: IHC (f, p), FACS
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.