MBP Monoclonal Antibody

• Catalog number
  A1033-100
• Price
  Please ask
• Size
  100 μg

• Antibody Target
  Mbp
• Target Alternative Name
  Myelin A1 protein, Myelin membrane encephalitogenic protein
• Antibody Type
  Monoclonal
• Clone
  4C6
• Species Reactivities
  Human
• Accession
  P04370
• Gene Id
  4155
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  100 ug (1 mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide.
• Purification
  Affinity purified mouse IgG using protein G
• Application
  WB
• Application And Usages
  Western blot
• Description
  The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  MBP   Monoclonal  
• Gene symbol
  MBP, PRG2, ENO1, HIVEP2, HIVEP1
• Short name
  MBP Monoclonal Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Isotype
  Mouse IgG
• Label
  mbp
• Alternative name
  MBP monoclonal (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6925
• Gene
  MBP
• Long gene name
  myelin basic protein
• Locus
  18q23
• Discovery year
  1986-01-01
• Entrez gene record
  4155
• Pubmed identfication
  • 2425357
• RefSeq identity
  • NM_001025081
• VEGA ID
  OTTHUMG00000132874

Gene info

• Identity
  HGNC:9362
• Gene
  PRG2
• Long gene name
  proteoglycan 2, pro eosinophil major basic protein
• Synonyms gene name
  • proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
• Synonyms
  • MBP
  • BMPG
  • proMBP
• Synonyms name
  • eosinophil major basic protein
• GenBank acession
  • BC005929
• Locus
  11q12.1
• Discovery year
  1993-09-29
• Entrez gene record
  5553
• Pubmed identfication
  • 1565101
• RefSeq identity
  • NM_002728
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000167027

Gene info

• Identity
  HGNC:3350
• Gene
  ENO1
• Long gene name
  enolase 1
• Synonyms gene
  • ENO1L1
  • MPB1
• Synonyms gene name
  • enolase 1, (alpha)
• Synonyms
  • PPH
  • MBP-1
• Synonyms name
  • alpha-enolase
• GenBank acession
  • BC022545
• Locus
  1p36.23
• Discovery year
  1989-04-21
• Entrez gene record
  2023
• Pubmed identfication
  • 9653645
  • 9691177
• RefSeq identity
  • NM_001428
• Classification
  • Enolases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000001773
• Locus Specific Databases
  • LRG_1165

Gene info

• Identity
  HGNC:4921
• Gene
  HIVEP2
• Long gene name
  HIVEP zinc finger 2
• Synonyms gene name
  • human immunodeficiency virus type I enhancer-binding protein 2
  • human immunodeficiency virus type I enhancer binding protein 2
• Synonyms
  • MBP-2
  • HIV-EP2
  • MIBP1
  • ZAS2
  • Schnurri-2
  • ZNF40B
• Synonyms name
  • c-myc intron binding protein 1
• GenBank acession
  • M60119
• Locus
  6q24.2
• Discovery year
  1992-10-21
• Entrez gene record
  3097
• Pubmed identfication
  • 1733857
  • 2022670
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000015713

Gene info

• Identity
  HGNC:4920
• Gene
  HIVEP1
• Long gene name
  HIVEP zinc finger 1
• Synonyms gene
  • ZNF40
• Synonyms gene name
  • human immunodeficiency virus type I enhancer-binding protein 1
  • zinc finger protein 40
  • human immunodeficiency virus type I enhancer binding protein 1
• Synonyms
  • CIRIP
  • MBP-1
  • CRYBP1
  • PRDII-BF1
  • ZAS1
  • Schnurri-1
  • ZNF40A
• GenBank acession
  • J05011
• Locus
  6p24.1
• Discovery year
  1990-10-04
• Entrez gene record
  3096
• Pubmed identfication
  • 2108316
  • 2037300
  • 2504707
• RefSeq identity
  • NM_002114
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000014265

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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