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PF 04554878 for cell activation

PF 04554878 for cell activation is available 0 time from Biovision labs

Other name N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide; Defactinib; VS-6063
Supplied with N/A
Description PF-04554878 is potent, ATP-competitive, focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. PF-04554878 inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.  A combination of PF-04554878 and paclitaxel markedly decreases proliferation and increases apoptosis.
Category Biochemicals
Molecular formula C₂₀H₂₁F₃N₈O₃S
Is it cell-permeable? Yes
Molecular weight 510.49
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 1073154-85-4
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance White solid
Reconstitute instructions DMSO (~40 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name PF-04554878 for activation
Technique activation
Alternative name PF-04554878 to measure cellular activation
Tissue cell
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