Anti-14-3-3 ZETA/DELTA
-
Catalog numberMBS222336
-
PricePlease ask
-
Size100ul
-
-
Alternative name1Anti-RABBIT ANTI 14-3-3 ZETA/DELTA
-
Alternative name2RABBIT ANTI 14-3-3 ZETA/DELTA
-
Alternative name3Lapin ANTI 14-3-3 ZETA/DELTA
-
Alternative name414-3-3 ZETA/DELTA
-
Alternative name5N/A
-
Other names14-3-3 protein zeta/delta; 14-3-3 protein zeta/delta; N/A; N/A; Protein kinase C inhibitor protein 1
-
Gene name14-3-3 ZETA/DELTA
-
Gene name synonimsN/A
-
Other gene namesN/A; YWHAZ; N/A; KCIP-1
-
CategoryAntibodies
-
ClonalityPolyclonal
-
Immunoglobulin isotypePolyclonal IgG
-
ClonePolyclonal antibody
-
Host organismRabbit
-
Species reactivitySheep
-
Specificity and cross reactivity14-3-3 ZETA/DELTA This item recognizes the acetylated N-terminal of 14-3-3 zeta and the phosphorylated zeta isoform (also known as 14-3-3 delta) in all mammals. These are members of the 14-3-3 family which consists of 30kDa proteins that are involved in multiple protein kinase signaling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isotypes and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 zeta is a susceptibility gene for paranoid schizophrenia and is overexpressed in the temporal cortex of cognitively impared Alzheimers patients. The protein binds yeast Sps1/Ste20-related kinase 1 (YSK1) and localizes to the golgi, possibly linking YSK1 signaling, protein transport, cell adhesion and migration. It co-localizes with epidermal growth factor receptor to the plasma membrane following epidermal growth factor signaling. The zeta isoform is involved in MAPKAPK2-mediated phosphorylation which may have a role in p38 MAPK-dependent inflammation. When bound to ADAM 22, 14-3-3 zeta is involved in cell adhesion. 14-3-3 zeta also interacts with cofilin, LIM-domain-containing protein kinase 1, protein kinase B/Akt and GPI alpha. 14-3-3 zeta can be phosphorylated at serine 184 to produce 14-3-3 delta. This item may not react with recombinant proteins that are not N-acetylated.
-
Purification methodN/A
-
Form AppearanceSerum (Serum - liquid)
-
ConcentrationN/A
-
Storage and shippingStore at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
-
Tested forWestern Blot (WB), ELISA (EIA), Immunohistology - Paraffin (IHC)
-
Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
-
AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Gene target
-
Gene symbolYWHAZ, YWHAQ, YWHAG, MIR1302-3, MIR509-3, MIR7-3, PIRC13, PIRC11
-
Short nameAnti-14-3-3 ZETA/DELTA
-
Techniqueanti-, anti, antibody to, antibodies
-
Alternative nameAntibody to14-3-3 ZETA/DELTA
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
-
Synonyms gene
-
Synonyms gene name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1993-09-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- 14-3-3 phospho-serine/phospho-threonine binding proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
-
Synonyms gene name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
- protein, theta
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-08-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- 14-3-3 phospho-serine/phospho-threonine binding proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
-
Synonyms gene name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1993-09-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- 14-3-3 phospho-serine/phospho-threonine binding proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1302-3
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1302 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 509-3
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2007-10-24
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR506 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 7-3
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR7 family
Gene info
-
Identity
-
Gene
-
Long gene namepiwi-interacting RNA cluster 13
-
Locus
-
Discovery year2009-11-05
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Piwi-interacting RNA clusters
Gene info
-
Identity
-
Gene
-
Long gene namepiwi-interacting RNA cluster 11
-
Locus
-
Discovery year2009-11-05
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Piwi-interacting RNA clusters
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
