PDGFRA(Tyr1018) Antibody

• Catalog number
  bs-3318R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PDGFRA(Tyr1018) Primary Polyclonal Antibody
• Also known as
  PDGFRA(Tyr1018) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PDGFRA Tyr1018
• Specificity
  This is a highly specific antibody against PDGFRA Tyr1018.
• Modification s
  Phosphorylation
• Modification site s
  Tyr1018
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human PDGF Receptor alpha around the phosphorylation site of Tyr1018 [SG(p-Y)II]
• Gene ID number
  5156
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PDGF Receptor alpha; Platelet–dirived growth factor receptor-alpha; Alpha platelet derived growth factor receptor; CD 140a; CD140a; CD140a antigen; MGC74795; PDGF alpha chain; PDGF R alpha; PDGFR 2; PDGFR A; PDGFR alpha; PDGFR2; PDGFRA; Platelet derived growth factor receptor 2; Platelet derived growth factor receptor alpha; Platelet derived growth factor receptor alpha polypeptide; PGFRA_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PDGFRA   Tyr1018  
• Gene symbol
  PDGFRA
• Short name
  Anti-PDGFRA Tyr1018
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PDGFRA(Tyr1018) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  platelet-derived growth factor receptor, alpha polypeptide, CD140A and PDGFR-2 and PDGFR2 and RHEPDGFRA, PDGFRA and IDBG-18854 and ENSG00000134853 and 5156, transferase activity, nuclei, Pdgfra and IDBG-171929 and ENSMUSG00000029231 and 18595, PDGFRA and IDBG-642308 and ENSBTAG00000007173 and 282301

Gene info

• Identity
  HGNC:8803
• Gene
  PDGFRA
• Long gene name
  platelet derived growth factor receptor alpha
• Synonyms gene name
  • platelet-derived growth factor receptor, alpha polypeptide
• Synonyms
  • CD140a
  • PDGFR2
  • GAS9
• GenBank acession
  • D50001
• Locus
  4q12
• Discovery year
  1989-05-19
• Entrez gene record
  5156
• Pubmed identfication
  • 8643452
• RefSeq identity
  • NM_006206
• Classification
  • I-set domain containing
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000128699
• Locus Specific Databases
  • LRG_309

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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