Caspase 4 Inhibitor Drug Screening Kit

Category

Research kit
Area of research

Cell Cycle & Cell Death
Form Buffer

Assay Kit containing the folllowing: 2X Reaction Buffer, Caspase Substrate LEVD-AFC (1 mM), DTT (1 M), Active Caspase-4 (Lyophilized), Caspase Inhibitor, Z-VAD-FMK (2 mM)
Storage

Store at -20 deg C
Shipping conditions

Blue Ice
Tested for

Functional Assay; IF; FC; ELISA
URL
More info
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Gene target

Caspase Inhibitor Drug Screening Kit
Short name

Caspase 4 Inhibitor Drug Screening Kit
Alternative name

Screening Kit for detection of Caspase 4 Inhibitor activity in the research laboratory
Alternative technique

kits
Alternative to gene target

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495