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anti-SREBP2 Antibody

anti-SREBP2 Antibody is available 1 time from Biovision labs

6966-100 | anti-SREBP2 Antibody size: SREBP2 Antibody | 407.59 USD

Catalog number 6966-100
Supplier Biovision
Price 407.59 USD
Size SREBP2 Antibody
1. Gene info
Identity 11290
Gene SREBF2
Long gene name sterol regulatory element binding transcription factor 2
Synonyms
  • SREBP2
  • bHLHd2
GenBank acession
  • U02031
Locus 22q13.2
Discovery year 1994-11-23
Entrez gene record 6721
Pubmed identfication
  • 7903453
RefSeq identity
  • NM_004599
Classification
  • Basic helix-loop-helix proteins
  • MicroRNA protein coding host genes
Havana BLAST/BLAT OTTHUMG00000151261
Product images
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Target of this antibody: SREBP2
Alternative names of antibody target: Sterol regulatory element-binding protein 2, SREBF2, Class D basic helix-loop-helix protein 2, bHLHd2, Sterol regulatory element-binding transcription factor 2, Processed sterol regulatory element-binding protein 2, SREBF2, BHLHD2, SREBP2
Background information: SREBP2 regulates cholesterol synthesis by activating the transcription of genes for HMG-CoA reductase and other enzymes of the cholesterol synthetic pathway.2 SREBP2 is ubiquitously detected in various tissues. Under basal conditions SREBP is bound to ER membranes as a glycosylated precursor protein. Upon cholesterol depletion, the protein is cleaved to its active forms (about 50-68 kDa) and translocated into the nucleus to stimulate transcription of genes involved in the uptake and synthesis of cholesterol.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit Ig
This antibody reacts with: Human
Immunogene sequence: This SREBF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the Central region of human SREBP2.
Concentration of antibody: N/A
Form of antibody: Liquid
Formulation of this antibody: In PBS with 0.09% (W/V) sodium azide.
Purification method: This antibody is purified through a protein A column, followed by peptide affinity purification
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: WB: ~1:1000, IF: 1:10-50, IHC-P: 1:10-50.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetSREBP2
Short name anti-SREBP2 Antibody
Technique Antibody, anti
Alternative name antibody to-SREBP2 (Antibody to)
Alternative technique antibodies
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anti-SREBP2 Antibody | Technique alternative | 01012194661
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