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Target antigen
Integrin alpha V
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
mouse, rat
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Analyses
WB,IHC-P,ICC
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Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin alpha V(1028-1048aa QEEQEREQLQPHENGEGNSET), identical to the related mouse and rat sequences.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the Integrin alpha V Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Integrin alpha V Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily(cytoadhesins). The human locus for the av gene(VNRA) was previously mapped to the long arm of chromosome 2. Sims et al.(2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.
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Related articles
1. Sosnoski DM, Emanuel BS, Hawkins AL, van Tuinen P, Ledbetter DH, Nussbaum RL, Kaos FT, Schwartz E, Phillips D, Bennett JS, et al. (Aug 1988). "Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa". J Clin Invest 81 (6): 1993–8. 2. Fernandez-Ruiz, E., de Villena, F. P.-M., Rodriguez de Cordoba, S., Sanchez-Madrid, F.Regional localization of the human vitronectin receptor alpha-subunit gene (VNRA) to chromosome 2q31-q32.Cytogenet. Cell Genet.62: 26-28, 1993.
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Gene Name
ITGAV
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Protein Name
Integrin alpha-V
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Gene Full Name
integrin, alpha V
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Synonyms
antigen identified by monoclonal antibody L230 antibody|CD 51 antibody|CD51 antibody|CD51 antigen antibody|DKFZp686A08142 antibody|HGNC antibody|integrin alpha V beta 3 antibody|integrin alpha-V antibody|Integrin alpha-V light chain antibody|integrin alphaVbeta3 antibody|integrin, alpha V(vitronectin receptor, alpha polypeptide, antigen CD51) antibody|ITAV_HUMAN antibody|ITGA V antibody|ITGAV antibody|Msk 8 antibody|Msk8 antibody|Vitronectin receptor alpha polypeptide antibody|Vitronectin receptor alpha polypeptide antigen CD51 antibody|Vitronectin receptor subunit alpha antibody|VNRA antibody|VTNR antibody
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Uniprot ID
P06756
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Description
The Integrin alpha V Antibody is a α- or alpha protein sometimes glycoprotein present in blood.
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
