Adrenergic Receptor Kinase, beta 1 (bARK1, B1 AR, ARK1 beta, G Protein Coupled Receptor Kinase 2, GPCR K2, GRK2)
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Catalog numberGEN606296
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PricePlease ask
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Size100ug
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Also known asAdrenergic Receptor Kinase, beta 1
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Other namesAdrenergic, beta, receptor kinase 1; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1; beta-ARK-1; OTTHUMP00000235171; G-protein coupled receptor kinase 2; adrenergic, beta, receptor kinase 1; G-protein coupled receptor kinase 2
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameADRBK1; ADRBK1; GRK2; BARK1; FLJ16718; BETA-ARK1; BARK; BARK1; GRK2
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Gene name synonimsADRBK1; ADRBK1; GRK2; BARK1; FLJ16718; BETA-ARK1; BARK; BARK1; GRK2
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Other gene namesADRBK1; ADRBK1; GRK2; BARK1; FLJ16718; BETA-ARK1; BARK; BARK1; GRK2
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2b
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Clone3G3
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens), Mammal, Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityReacts with mammalian b-adrenergic receptor kinase. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein A affinity chromatography.
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Form AppearanceSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide, before the addition of glycerol to 40%.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
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Tested applicationsELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolGRK2, OXER1, HCAR1, GPBAR1, AURKA, GPER1
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Short nameAdrenergic Receptor Kinase, beta 1 (bARK1, B1 AR, ARK1 beta, G Protein Coupled Receptor Kinase 2, GPCR K2, GRK2)
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Alternative nameAnti-Adrenergic Receptor Kinase, beta 1 (bARK1, B1 AR, ARK1 beta, G Protein Coupled Receptor Kinase 2, GPCR K2, GRK2)
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Gene info
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Identity
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Gene
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Long gene nameG protein-coupled receptor kinase 2
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Synonyms gene
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Synonyms gene name
- adrenergic, beta, receptor kinase 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-03-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- AGC family kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameoxoeicosanoid receptor 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-04-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Leukotriene receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namehydroxycarboxylic acid receptor 1
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Synonyms gene
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Synonyms gene name
- G protein-coupled receptor 104
- G protein-coupled receptor 81
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-01-20
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Entrez gene record
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Pubmed identfication
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Classification
- Hydroxycarboxylic acid receptors
Gene info
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Identity
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Gene
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Long gene nameG protein-coupled bile acid receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-01-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein-coupled bile acid receptor
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameaurora kinase A
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Synonyms gene
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Synonyms gene name
- serine/threonine kinase 15
- serine/threonine kinase 6
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-10-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameG protein-coupled estrogen receptor 1
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Synonyms gene
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Synonyms gene name
- G protein-coupled receptor 30
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein-coupled estrogen receptor
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Laboratory techniques that involve the in-vitro synthesis of many copies of DNA or RNA from one original template.
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Tree numbers
- E05.393.620
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data