ML141

• Catalog number
  2267-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  4-[4,5-Dihydro-5-(4-methoxyphenyl)-­3-phenyl-1H-pyrazol-1-yl]benzenesulfonamide’; CID2950007
• Description
  Cell-permeable. A potent, selective, reversible and non-competitive inhibitor of Cdc42 GTPase (IC₅₀ = 2.6 and 5.4 μM for Cdc42 wild type and activated mutant, respectively). No appreciable inhibitory activity up to 100 μM was observed with Rac1, Rab2, Rab7 or Ras in the multiplex screen.
• CAS Number
  71203-35-5
• Structure Available
  Yes
• Peptide sequence
  No
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₁N₃O₃S
• Molecular Weight
  407.49
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~30 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  A Cdc42 GTPase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD05987165
• PubChem CID
  2950007
• PubChem CID Link
• SMILES
  COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4
• InChi
  InChI=1S/C22H21N3O3S/c1-28-19-11-7-17(8-12-19)22-15-21(16-5-3-2-4-6-16)24-25(22)18-9-13-20(14-10-18)29(23,26)27/h2-14,22H,15H2,1H3,(H2,23,26,27)
• InChi Key
  QBNZBMVRFYREHK-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  ML141  
• Short name
  ML141
• Alternative name
  ML141

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