CD83, human recombinant

• Catalog number
  7344-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  CD83 antigen isoform b precursor, BL11, HB15
• Alternative_names
  CD83 antigen isoform b precursor, BL11, HB15
• Description
  Involved in the regulation of antigen presentation
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥90%
• Assay
  SDS-PAGE
• Molecular Weight
  16 kDa (148 aa, 20-144 aa + His Tag), confirmed by MALDI-TOF.
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  0.25 mg/ml
• Appearance
  Liquid
• Physical form description
  0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl and 30% glycerol.
• Background Information
  CD83 is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. Recombinant human CD83 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Amino acid sequence
  MGSSHHHHHH SSGLVPRGSH MGSTPEVKVA CSEDVDLPCT APWDPQVPYT VSWVKLLEGG EERMETPQED HLRGQHYHQK GQNGSFDAPN ERPYSLKIRN TTSCNSGTYR CTLQDPDGQR NLSGKVILRV TGCPAQRKEE TFKKYRAE
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CD83  
• Gene symbol
  CD83
• Short name
  CD83, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  CD83 molecule, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  CD83 molecule, BL11 and HB15, CD83 and IDBG-62750 and ENSG00000112149 and 9308, protein binding, Cell surfaces, Cd83 and IDBG-147707 and ENSMUSG00000015396 and 12522, CD83 and IDBG-636028 and ENSBTAG00000031430 and 617034

Gene info

• Identity
  HGNC:1703
• Gene
  CD83
• Long gene name
  CD83 molecule
• Synonyms gene name
  • CD83 antigen (activated B lymphocytes, immunoglobulin superfamily)
  • CD83 molecule
• Synonyms
  • HB15
  • BL11
• GenBank acession
  • Z11697
• Locus
  6p23
• Discovery year
  1999-03-26
• Entrez gene record
  9308
• Pubmed identfication
  • 1378080
  • 8422464
• Classification
  • CD molecules
  • V-set domain containing
• VEGA ID
  OTTHUMG00000014283

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