Anti-E-Cadherin (CDH1) Rabbit Monoclonal Antibody

• Catalog number
  A1126-50
• Price
  Please ask
• Size
  50 µl

• Antibody Target
  CDH1
• Target Alternative Name
  P-cadherin, N-Cadherin, E-Cadherin, K-Cadherin, M-jadherin, R-Cadherin
• Antibody Type
  Monoclonal
• Clone
  RM244
• Species Reactivities
  Human
• Immunogen Sequence
  A peptide corresponding to Cadherin-1
• Accession
  P12830
• Gene Id
  999
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
• Purification
  Affinity purified using protein A
• Application
  IHC, WB
• Positive Control
  WB: MCF-7 cells; IHC: human breast cancer tissues
• Application And Usages
  IHC: 1:500 -1:1000 dilution; WB: 1:1000 - 1:2000 dilution
• Description
  Cadherins comprise a family of Ca-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal domains. The relative short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rabbits are used for polyclonal antibody production by Biovision. Rabbit antibodies are very stable and can be stored for several days at room temperature. Biovision adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  E-Cadherin   CDH1   Monoclonal  
• Gene symbol
  CDH1, FZR1
• Short name
  Anti-E-Cadherin (CDH1) Rabbit Monoclonal Antibody
• Technique
  Antibody, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Rabbit, Rabbits
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toE-Cadherin (cadherin 1, type 1, E-cadherin (epithelial)) production species: rabbit monoclonal (antibody to-)
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  cadherin 1, type 1, E-cadherin (epithelial), Arc-1 and CD324 and CDHE and ECAD and LCAM and UVO, CDH1 and IDBG-38622 and ENSG00000039068 and 999, cell adhesion molecule binding, Extracellular, Cdh1 and IDBG-190074 and ENSMUSG00000000303 and 12550, BT.64827 and IDBG-634263 and ENSBTAG00000015991 and 282637

Gene info

• Identity
  HGNC:1748
• Gene
  CDH1
• Long gene name
  cadherin 1
• Synonyms gene
  • UVO
• Synonyms gene name
  • cadherin 1, type 1, E-cadherin (epithelial)
• Synonyms
  • uvomorulin
  • CD324
• Synonyms name
  • E-Cadherin
• GenBank acession
  • L08599
• Locus
  16q22.1
• Discovery year
  1986-01-01
• Entrez gene record
  999
• Pubmed identfication
  • 9925936
• RefSeq identity
  • NM_004360
• Classification
  • CD molecules
  • Type I classical cadherins
• VEGA ID
  OTTHUMG00000137561
• Locus Specific Databases
  • LRG_301

Gene info

• Identity
  HGNC:24824
• Gene
  FZR1
• Long gene name
  fizzy and cell division cycle 20 related 1
• Synonyms gene name
  • fizzy/cell division cycle 20 related 1 (Drosophila)
  • fizzy/cell division cycle 20 related 1
• Synonyms
  • HCDH1
  • CDH1
  • HCDH
  • FZR
  • FZR2
  • KIAA1242
  • CDC20C
• Synonyms name
  • CDC20 homolog 1
• GenBank acession
  • AF083810
• Locus
  19p13.3
• Discovery year
  2004-03-31
• Entrez gene record
  51343
• Pubmed identfication
  • 9734353
  • 11003657
• RefSeq identity
  • NM_016263
• Classification
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000180747

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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