Thrombin Activity Fluorometric Assay Kit
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Catalog number
K373-100
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Price
Please ask
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Size
100 assays
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Summary
• Detection method- Fluorescence (Ex/Em = 350/450 nm) • Applications- Determine activity of pure Thrombin - Detect the activity of Thrombin in plasma
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Detection Method
Fluorescence (Ex/Em = 350/450 nm)
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Applications
• Determine activity of pure Thrombin • Detect the activity of Thrombin in plasma
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Sample Type
Plasma
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Features Benefits
• Simple & convenient protocol. • Can detect thrombin activity as low as . • Kit contains all necessary reagents for measuring thrombin activity.
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Storage Conditions
-20°C
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Shipping Conditions
gel pack
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Shelf life
12 months
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Background
Thrombin enzyme (Factor IIa, EC 3.4.21.5), a Serine protease, is an important clotting factor in the coagulation cascade that involves the conversion of soluble fibrinogen to insoluble active fibrin strands. In this pathway, Prothrombin is proteolytically converted into an active Thrombin. Thrombin is also a potent vasoconstrictor and mitogen implicated as a major factor in vasospasm following subarachnoid hemorrhage. Ruptured cerebral aneurysm blood clots around a cerebral artery releases thrombin, which in turn induces acute and prolonged narrowing of the blood vessel, potentially resulting in cerebral ischemia and infarction (stroke). In addition, it is a pro-inflammatory enzyme that may influence the onset and progression of atherosclerosis. Biovision's Thrombin activity assay kit utilizes the ability of Thrombin to proteolytically cleave a synthetic substrate and release a fluorophore, AMC, which can be easily quantified by fluorescence reader. This assay kit is simple, rapid and can detect Thrombin activity as low as 1 ng in samples.
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Test
Biovision supplies other types of Assays as 1.
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Gene target
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Short name
Thrombin Activity Fluorometric Assay Kit
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Technique
Assay, assays
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Host
Assay
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Alternative name
Thrombin Activity fluorescence test reagent
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Alternative technique
arrays, kits
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Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Product images
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