anti-JMJD1C Antibody

• Catalog number
  5371
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  JMJD1C Antibody: The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.
• Gene names
  JMJD1C Antibody: TRIP8, JHDM2C, KIAA1380, TRIP8, Probable JmjC domain-containing histone demethylation protein 2C, Jumonji domain-containing protein 1C, TR-interacting protein 8
• Antibodie s label
  unlabelled serum
• Purity
  JMJD1C Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  This antibody will not cross-react with JMJD1A or JMJD1B.
• Antigen
  JMJD1C antibody was made against a 20 amino acid synthetic peptide from near the amino terminus of human JMJD1C.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  JMJD1C antibody can be used for detection of JMJD1C by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  JMJD1C Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  JMJD1C antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  118600981
• Ncbi nr
  NP_116165
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  221037
• GENE symbol
  JMJD1C
• Antigene name
  jumonji domain containing 1C
• Source
  Homo sapiens
• Protein nr
  Q15652
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  JMJD1C  
• Gene symbol
  JMJD1C-AS1, JMJD1C
• Short name
  anti-JMJD1C Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toJMJD1C (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:28222
• Gene
  JMJD1C-AS1
• Long gene name
  JMJD1C antisense RNA 1
• GenBank acession
  • AK314171
• Locus
  10q21.3
• Discovery year
  2013-02-07
• Entrez gene record
  84989
• Pubmed identfication
  • 12477932
• RefSeq identity
  • NR_027182
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000186280

Gene info

• Identity
  HGNC:12313
• Gene
  JMJD1C
• Long gene name
  jumonji domain containing 1C
• Synonyms gene
  • TRIP8
• Synonyms gene name
  • thyroid hormone receptor interactor 8
• Synonyms
  • DKFZp761F0118
  • KIAA1380
  • FLJ14374
  • KDM3C
• GenBank acession
  • L40411
• Locus
  10q21.3
• Discovery year
  1999-03-19
• Entrez gene record
  221037
• Pubmed identfication
  • 7776974
  • 24240613
  • 31076406
• RefSeq identity
  • NM_004241
• Classification
  • Lysine demethylases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000018311

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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