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Synonyms
TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
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Alternative_names
TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
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Description
Plays an important role in CD4+ and CD8+ T-cells and B-cells response.
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Recombinant
Yes
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Source
HEK 293 cells
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Purity by SDS PAGE
> 90%
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Assay
SDS-PAGE
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Endotoxin Level
< 1.0 EU per/ug
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Molecular Weight
47.7 kDa
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Physical form description
Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
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Reconstitution Instructions
Reconstitute in sterile deionized water to the desired protein concentration.
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Background Information
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
TNFRSF4
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Short name
CellExp™ OX40 / TNFRSF4 / CD134, Fc Tag, recombinant
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Technique
Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Host
Rat
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Label
Fc Tag
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Species
Humans, Rats
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Alternative name
H. sapiens CellExp™ OX40 / tumor necrosis factor receptor superfamily, member 4 / CD134, fragment c detection labelled, rat Rec.
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Alternative technique
rec
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Alternative to gene target
tumor necrosis factor receptor superfamily, member 4, ACT35 and CD134 and IMD16 and OX40 and TXGP1L, TNFRSF4 and IDBG-84605 and ENSG00000186827 and 7293, protein binding, Cell surfaces, Tnfrsf4 and IDBG-208242 and ENSMUSG00000029075 and 22163, TNFRSF4 and IDBG-635323 and ENSBTAG00000015635 and 528782
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