-
Products_type
Active Protein
-
Products_short_name
[Platelet Derived Growth Factor Receptor alpha, extracellular domain Human]
-
Products_name_syn
[Platelet Derived Growth Factor Receptor alpha, extracellular domain, Recombinant Human_x000B_(PDGFRA, Platelet-Derived Growth Factor Receptor, alpha polypeptide, Alpha Platelet-Derived Growth Factor Receptor precursor, CD140a, CD140A, CD140a antigen, MGC74795,]
-
Other_names
[platelet-derived growth factor subunit A isoform 1 preproprotein; Platelet-derived growth factor subunit A; platelet-derived growth factor subunit A; PDGF-1; PDGF A-chain; PDGF subunit A; platelet-derived growth factor A chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha isoform 2 preproprotein; platelet-derived growth factor alpha polypeptide; PDGF-1; Platelet-derived growth factor A chain; Platelet-derived growth factor alpha polypeptide]
-
Other_gene_names
[PDGFA; PDGFA; PDGF1; PDGF-A; PDGF1; PDGF subunit A]
-
Purity
Affinity PurifiedPurified by lectin affinity chromatography.
-
Form
Supplied as a lyophilized powder in PBS, 10mM Tris-HCl, pH 7.0
-
Storage_stability
Lyophilized powder may be stored at -20 degree C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
-
Description
The Platelet Derived Growth Factor Receptor alpha, extracellular domain, Recombinant (PDGFRA, Platelet-Derived Growth Factor Receptor, alpha polypeptide, Alpha Platelet-Derived Growth Factor Receptor , CD140a, CD140A, CD140a antigen, MGC74795, is a α- or alpha protein sometimes glycoprotein present in blood. Antigens are peptides or recombinant or native dependent on the production method. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
PDGFRA
-
Short name
Platelet Derived Growth Factor Receptor alpha, extracellular domain, Recombinant (PDGFRA, Platelet-Derived Growth Factor Receptor, alpha polypeptide, Alpha Platelet-Derived Growth Factor Receptor , CD140a, CD140A, CD140a antigen, MGC74795,
-
Technique
Recombinant, antigen, antigenes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
Host
Sf9
-
Species
Human, Humans
-
Alternative name
Platelet Derived Growth Factor Receptor a, extracellular domain, Rec. H. sapiens (platelet-derived growth factor receptor, a polypeptide, Platelet-Derived Growth Factor Receptor, a multipeptide, a Platelet-Derived Growth Factor Receptor precursor, CD140a, CD140A, CD140a protein, MGC74795,
-
Alternative technique
rec, antigenes
-
Alternative to gene target
platelet-derived growth factor receptor, alpha polypeptide, CD140A and PDGFR-2 and PDGFR2 and RHEPDGFRA, PDGFRA and IDBG-18854 and ENSG00000134853 and 5156, transferase activity, nuclei, Pdgfra and IDBG-171929 and ENSMUSG00000029231 and 18595, PDGFRA and IDBG-642308 and ENSBTAG00000007173 and 282301
-