Filters
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing

MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-a Antibody

MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-a Antibody is available 1 time from Mbs polyclonals labs

MBS644349 | MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-a Antibody size: 200ul | 679.04 USD

1. Gene info
Identity6838
Long gene name microtubule associated protein 1 light chain 3 alpha
Discovery year 2000-06-29
Entrez gene record84557
Pubmed identfication
RefSeq identity
Classification
  • Autophagy related
Havana BLAST/BLATOTTHUMG00000032306
2. Gene info
Identity13352
Long gene name microtubule associated protein 1 light chain 3 beta
Synonyms
GenBank acession
Locus16q24.2
Discovery year 2002-09-16
Entrez gene record81631
Classification
  • Autophagy related
Havana BLAST/BLATOTTHUMG00000137654
3. Gene info
Identity6835
GeneMAP1A
Long gene name microtubule associated protein 1A
Synonyms gene
GenBank acession
Locus15q15.3
Discovery year 1992-07-09
Entrez gene record4130
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000059756
4. Gene info
Identity6836
GeneMAP1B
Long gene name microtubule associated protein 1B
Synonyms
GenBank acession
Locus5q13.2
Discovery year 1992-02-06
Entrez gene record4131
Pubmed identfication
RefSeq identity
Classification
  • Protein phosphatase 1 regulatory subunits
Havana BLAST/BLATOTTHUMG00000100952
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedData report embryonic expression patterns for LC3alpha and LC3beta, with some overlap but notable differences in the brain, and in tissues of non-neuronal origin.
LC3 was colocalized with the H2-DM-positive lysosomal compartments in both cortical and medullary thymic epithelial cell lines
Mycobacterium marinum lacking the region of difference 1 (RD1) is unable to recruit LC3, indicating that a functional ESX-1 secretion system is an absolute requirement for this process.
inhibition of proteasomal degradation results in increased oligomerization and activation of caspase-8 on intracellular membranes; enhanced caspase-8 oligomerization and activation are promoted through interaction with SQSTM1/p62 and (LC3)
Data show that luminal P-PERK and LC3 levels are reduced in PERK-deficient mammary glands, whereas they are increased in human breast ductal carcinoma in situ.
The effect of chronic infection with Heligmosomoides polygyrus on autophagy is associated with decreased expression and processing of LC3, a key component of the autophagic machinery.
PRIP is a novel LC3-binding protein that acts as a negative modulator of autophagosome formation.
Deleting Atg7 or Atg5 or blocking LC3 lipidation or ATG5-ATG12 conjugation decreases ERK phosphorylation.
LC3 overexpression thus exerts neuroprotection through increasing alpha7nAChR expression for eAbeta binding and further enhancing autophagic activity for Abeta clearance in vitro and in vivo.
LC3 overexpression in 3T3-L1 preadipocytes stimulates adipocyte differentiation via direct modulation of RKIP-dependent ERK1 activity.
Clonality Polyclonal
Host organism Host: Rabbit; Source: Human
Other names N/A
Category Antibodies
Form/Appearance Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Description productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
Alternative name3 MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-a
Alternative name2 MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-a
Alternative name5 Anti -MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-a
Alternative name4 MAPG8a/b
Other gene names N/A
Immunoglobulin isotype IgG
Alternative name1 Anti-MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-a
Species reactivity Human, Mouse
Gene name N/A
Clone Polyclonal antibody
Gene name synonims N/A
Concentration N/A
Specificity and cross-reactivity Human, mouse
Purification method Affinity Purified by Protein A affinity chromatography.
Advisory In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Storage and shipping Store at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested for: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Properties If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Short name MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy- protein LC3 B, Autophagy- ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-a Antibody
Technique Antibody, light
Alternative name MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associated proteins 1A/1B light epitope 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light epitope 3-like protein 2, MAP1A/MAP1B light epitope 3 B, Microtubule-a (Antibody to)
Alternative technique antibodies
Similar products
Ask
Ajax processing
Close
MAPG8a/b (MAP1LC3A/B, MAP1LC3B, MAP1ALC3, Microtubule-associ
Filters
+32-(0)1-658-90-45 lieven@gentaur.com
Contact us
Ajax processing
Close
Chat with gentaur.com employee