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Synonyms
Resistin-like β, RELM β, Cysteine-rich secreted protein FIZZ2, Colon and small intestine-specific cysteine-rich protein, Cysteine-rich secreted protein A12-α-like 1, Colon carcinoma-related gene protein, RELM-b, XCP2, HXCP2
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Alternative_names
Resistin-like β, RELM β, Cysteine-rich secreted protein FIZZ2, Colon and small intestine-specific cysteine-rich protein, Cysteine-rich secreted protein A12-α-like 1, Colon carcinoma-related gene protein, RELM-b, XCP2, HXCP2
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Description
Colon and small intestine-specific cysteine-rich protein
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Recombinant
Yes
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Source
E. coli
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Purity
≥95%
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Biological activity
Test in process
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Molecular Weight
11.0 kDa
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Storage Temp
-20°C
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Shipping
Blue ice
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Shelf Life
12 months
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Appearance
Lyophilized protein
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Physical form description
Sterile filtered and lyophilized with no additives
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Reconstitution Instructions
Reconstitute to 1 mg/ml with sterilized dH₂O. Pipet to dissolve the protein pellet completely.
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Background Information
Human RELM β (Resistin-like molecule β/FIZZ2) is a new member to the family of adipocyte secreted proteins called adipocytokines. This family includes the RELM α, RELM β and Resistin molecules. Interestingly, RELM β and Resistin share similar characteristics such as an additional cysteine residue within the variable N-terminal region and are both homodimeric proteins. However, the RELM β is expressed only in the gastrointestinal track; especially the colon, while the Resistin and RELM β are secreted exclusively by adipocytes. Currently, the biological function of these proteins, as well as their molecular targets is largely unknown. Recombinant Human RELM β is a disulfide-linked homodimer with a total molecular weight of 11.0 kDa, consisting of 90 amino acid residue chains.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants