Anti-Corin (Polyclonal), ALEXA Fluor 594
-
Catalog numberGENTObs-7685R-A594
-
PricePlease ask
-
Size100 microliters
-
-
TypeConjugated Primary Antibody
-
Conjugated withALEXA FLUOR® 594
-
Host organismRabbit (Oryctolagus cuniculus)
-
Target Protein PeptideCorin
-
SpecificityThis antibody reacts specifically with Corin
-
ModificationNo modification has been applied to this antibody
-
Modification siteNone
-
ClonalityPolyclonal Antibody
-
ClonePolyclonal Antibodies
-
Concentration1ug per 1ul
-
Subcellular locationsExtracellular
-
Antigen SourceKLH conjugated synthetic peptide derived from human Corin
-
Gene ID10699
-
Swiss ProtQ9Y5Q5
-
ApplicationsIF(IHC-P)
-
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
-
Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
-
Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
-
Background informationSerine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
-
Purification methodPurified by Protein A.
-
StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
-
Excitation emission590nm/617nm
-
SynonymsCRN; ATC2; Lrp4; PEE5; TMPRSS10; Atrial natriuretic peptide-converting enzyme; Corin; Heart-specific serine proteinase ATC2; Pro-ANP-converting enzyme; Transmembrane protease serine 10
-
Also known asCorin Polyclonal Antibody
-
Other nameAnti-Corin Polyclonal
-
AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
PropertiesFor facs or microscopy Alexa 1 conjugate.
-
ConjugationAlexa Fluor, ALEXA FLUOR® 594
-
ConjugatedAlexa conjugate 1
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
Gene target
-
Gene symbolCORIN
-
Short nameAnti-Corin
-
TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 594
-
Alternative nameCorin Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
-
Alternative techniquepolyclonals, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namecorin, serine peptidase
-
Synonyms gene name
- corin, serine protease
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2004-05-10
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Scavenger receptor cysteine rich domain containing
- Type II transmembrane serine proteases
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data