Soluble RANK Ligand Protein

Storage

For short term storage Soluble RANK Ligand Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius.
Tips

Due to handling and transportation, small amounts of the Soluble RANK Ligand Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance.
Description

FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

Identity

HGNC:20763
Gene

ANKFY1
Long gene name

ankyrin repeat and FYVE domain containing 1
Synonyms
- ANKHZN
- KIAA1255
- ZFYVE14
- BTBD23
- RANK-5
Synonyms name
- rabankyrin-5
GenBank acession
- AB033081
Locus

17p13.2
Discovery year

2003-04-29
Entrez gene record

51479
Pubmed identfication
- 10940552
- 17273843
RefSeq identity
- NM_016376
Classification
- Zinc fingers FYVE-type
- BTB domain containing
- Ankyrin repeat domain containing
VEGA ID

OTTHUMG00000177727

Identity

HGNC:11908
Gene

TNFRSF11A
Long gene name

TNF receptor superfamily member 11a
Synonyms gene
- PDB2
- LOH18CR1
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 11a, activator of NFKB
- Paget disease of bone 2
- loss of heterozygosity, 18, chromosomal region 1
- tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Synonyms
- RANK
- CD265
- FEO
- ODFR
- TRANCE-R
Synonyms name
GenBank acession
- AF018253
Locus

18q21.33
Discovery year

1998-12-04
Entrez gene record

8792
Pubmed identfication
- 9367155
- 10615125
Classification
- CD molecules
- Tumor necrosis factor receptor superfamily
VEGA ID

OTTHUMG00000132779
Locus Specific Databases
- LRG_194