Recombinant Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)

• Catalog number
  RPU44262-50ug
• Price
  Please ask
• Size
  50ug

• Estimated Turnaround Time
  6-11 business days
• Gene Name
  NA
• Alternative Names
  CD253; TNFSF10; APO2L; Apo2-L; TL2; TRAIL; Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand
• Source
  E.coli
• Purity
  ≥ 98%
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Shipping Conditions
  Ice packs
• Storage conditions
  Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
• Shelf life
  1 year
• Restriction
  For research use only. Not for diagnostic procedures.
• Description
  This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Tumor   Necrosis   Factor   Related   Ligand   TRAIL  
• Gene symbol
  TNFSF10, TNFRSF10B
• Short name
  Recombinant Tumor Necrosis Factor Apoptosis Ligand (TRAIL)
• Technique
  Recombinant, apoptosis, apoptosis pathway, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Rattus norvegicus (Rat)
• Alternative name
  Rec. Tumor Necrosis Factor Related programmed cellular destruction Inducing Ligand (TRAIL)
• Alternative technique
  rec, celldeath
• Tissue
  tumor

Gene info

• Identity
  HGNC:11925
• Gene
  TNFSF10
• Long gene name
  TNF superfamily member 10
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 10
• Synonyms
  • TRAIL
  • Apo-2L
  • TL2
  • CD253
• GenBank acession
  • U37518
• Locus
  3q26
• Discovery year
  1998-12-04
• Pubmed identfication
  • 8777713
  • 8663110
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000156917

Gene info

• Identity
  HGNC:11905
• Gene
  TNFRSF10B
• Long gene name
  TNF receptor superfamily member 10b
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10b
• Synonyms
  • DR5
  • KILLER
  • TRICK2A
  • TRAIL-R2
  • TRICKB
  • CD262
  • TRAILR2
• GenBank acession
  • AF012628
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8795
• Pubmed identfication
  • 9285725
  • 9311998
• RefSeq identity
  • NM_147187
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000097826

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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