AMI-5

  • Catalog number
    2300-250
  • Price
    Please ask
  • Size
    250 mg
  • Alternative_name
    2′,4′,5′,7′-Tetrabromofluorescein disodium salt, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish
  • Description
    AMI-5 is a non-specific small molecule inhibitor of protein arginine methyltransferases (PRMTs) (IC₅₀ = 0.78 and 1.41 µM against Hmt1p and PRMT1, respectively) and histone lysine methyltransferases (HKMTs) (DOT1 and SET7, but not Suv39H1 and Suv39H2).
  • CAS Number
    17372-87-1
  • Structure Available
    Yes
  • Peptide sequence
    No
  • Salt Form
    No
  • Molecular Formula
    C₂₀H₆Br₄Na₂O₅
  • Molecular Weight
    691.85
  • Cell Permeable
    No
  • Purity
    ≥90% (based on the anhydrous material)
  • Solubilities
    H2O (1 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A protein methyltransferase inhibitor
  • Storage Condition
    +4 ÌŠC
  • Shipping Condition
    gel pack
  • Shelf Life
    60 months
  • MDL Number
    MCFD00005040
  • PubChem CID
    11048
  • SMILES
    C1=CC=C(C(=C1)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)Br)[O-])Br)Br)Br)C(=O)[O-].[Na+].[Na+]
  • InChi
    InChI=1S/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2
  • InChi Key
    SEACYXSIPDVVMV-UHFFFAOYSA-L
  • MSDS Available
    Yes
  • Gene target
    AMI-5  
  • Gene symbol
    MIR1302-5, PIRC23, PIRC22, PIRC20, PIRC21, HTR6, IGHV2OR16-5, IGKV3OR2-5, SNORD116-5, TGFB1I1
  • Short name
    AMI-5
  • Alternative name
    AMI-5
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    piwi-interacting RNA cluster 23
  • Locus
    5
  • Discovery year
    2009-11-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
Gene info
  • Identity
  • Gene
  • Long gene name
    piwi-interacting RNA cluster 22
  • Locus
    5
  • Discovery year
    2009-11-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
Gene info
  • Identity
  • Gene
  • Long gene name
    piwi-interacting RNA cluster 20
  • Locus
    5
  • Discovery year
    2009-11-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
Gene info
  • Identity
  • Gene
  • Long gene name
    piwi-interacting RNA cluster 21
  • Locus
    5
  • Discovery year
    2009-11-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
Gene info
  • Identity
  • Gene
  • Long gene name
    5-hydroxytryptamine receptor 6
  • Synonyms gene name
    • 5-hydroxytryptamine (serotonin) receptor 6
    • 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1997-12-11
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • 5-hydroxytryptamine receptors, G protein-coupled
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin kappa variable 3/OR2-5 (pseudogene)
  • Synonyms gene name
    • immunoglobulin kappa variable 3/OR2-5
    • immunoglobulin kappa variable 3/OR2-5 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-18
  • Entrez gene record
  • Classification
    • Immunoglobulin kappa (IGK) orphons
  • VEGA ID
Gene info
Gene info
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