Human CellExp™ Integrin alpha 6 beta 1 Heterodimer, Human Recombinant

• Catalog number
  P1203-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Integrin alpha 6 beta 1, ITGA6B1, ITGA6&ITGB1, CD49f, VLA-6
• Alternative_names
  Integrin alpha 6 beta 1, ITGA6B1, ITGA6&ITGB1, CD49f, VLA-6
• Description
  Hetrodimer integrin (alpha 6 beta 1) negatively regulate erbB2/HER2 signaling
• Recombinant
  Yes
• Source
  HEK293 cells
• Purity by SDS PAGE
  > 90%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Molecular Weight
  116.8 kDa, 83.7 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute in sterile deionized water to the desired protein concentration.
• Background Information
  Integrin alpha 6 beta 1, also called platelet glycoprotein GPIc-IIa, is a receptor for laminin on platelets. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. ITGA6 has been shown to interact with TSPAN4 and GIPC1.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional description
  The CellExp™ Integrin alpha 6 beta 1 Heterodimer, Recombinant is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   Integrin   alpha   beta   Heterodimer  
• Short name
  CellExp™ Integrin alpha 6 beta 1 Heterodimer, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ Integrin a 6 b 1 Heterodimer, H. sapiens Rec.
• Alternative technique
  rec

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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