Recombinant Vaccinia virus Serine proteinase inhibitor 3 (SPI-3)

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Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Vaccinia virus Serine proteinase inhibitor SPI-3
Gene symbol

SPIB, SPI1, SPIC, MIR1302-3, MIR509-3, MIR7-3, PIRC13, PIRC11
Short name

Recombinant Vaccinia virus Serine proteinase inhibitor 3 (SPI-3)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Virus, Viruses
Alternative name

Rec. Vaccinia virus Serine proteinase suppressor 3 (SPI-3)
Alternative technique

rec
Virus

vaccinia

Identity

HGNC:11241
Gene

SPI1
Long gene name

Spi-1 proto-oncogene
Synonyms gene name
- spleen focus forming virus (SFFV) proviral integration oncogene
Synonyms
- PU.1
- SPI-A
- OF
- SFPI1
- SPI-1
Synonyms name
- hematopoietic transcription factor PU.1
- 31 kDa transforming protein
GenBank acession
- X52056
Locus

11p11.2
Discovery year

1988-07-04
Entrez gene record

6688
Pubmed identfication
- 1693183
RefSeq identity
- NM_003120
Classification
- ETS transcription factor family
VEGA ID

OTTHUMG00000150150

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data