M-CSF Receptor(Tyr546) Antibody, FITC Conjugated
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Catalog numberbs-3074R-FITC
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PricePlease ask
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Size0.1ml
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Long nameM-CSF Receptor(Tyr546) Antibody, FITC Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationFITC
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenM-CSF Receptor Tyr546
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SpecificityThis is a highly specific antibody against M-CSF Receptor Tyr546.
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ModificationPhosphorylation
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Modification siteTyr546
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 546
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Gene ID number1436
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundThis protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission494nm/518nm
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SynonymsC FMS; CD 115; CD115; CD115 antigen; CFMS; Colony stimulating factor 1 receptor; Colony stimulating factor I receptor; CSF 1 R; CSF 1R; CSF1 R; CSF1R; CSFR; FIM 2; FIM2; CSF1R_HUMAN
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
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Additional conjugationAnti-FITC Antibody
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolCSF1, CPT1B, CSF2, IRAK3, PGAM2, CYP20A1, USP16, CYB5B, H3C14, CSF3
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Short nameAnti-M-CSF Receptor Tyr546
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TechniqueAntibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
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IsotypeImmunoglobulin G (IgG)
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LabelFITC
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Alternative nameAnti-M-CSF Receptor Tyr546 PAb FITC
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Alternative techniqueantibodies, fluorescine
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Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 1
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Synonyms gene name
- colony stimulating factor 1 (macrophage)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecarnitine palmitoyltransferase 1B
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Synonyms gene name
- carnitine palmitoyltransferase 1B (muscle)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-08-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 2
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Synonyms gene name
- colony stimulating factor 2 (granulocyte-macrophage)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 receptor associated kinase 3
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Synonyms gene name
- interleukin-1 receptor-associated kinase 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-07-17
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Entrez gene record
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Pubmed identfication
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Classification
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephosphoglycerate mutase 2
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Synonyms gene name
- phosphoglycerate mutase 2 (muscle)
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Synonyms
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Classification
- Phosphoglycerate mutases
- Bisphosphoglycerate phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecytochrome P450 family 20 subfamily A member 1
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Synonyms gene name
- cytochrome P450, family 20, subfamily A, polypeptide 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-03-20
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Entrez gene record
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RefSeq identity
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Classification
- Cytochrome P450 family 20
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameubiquitin specific peptidase 16
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Synonyms gene name
- ubiquitin specific protease 16
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-07-09
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Pubmed identfication
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Classification
- Ubiquitin specific peptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecytochrome b5 type B
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Synonyms gene name
- cytochrome b5 type B (outer mitochondrial membrane)
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Synonyms
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Locus
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Discovery year2006-01-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3 clustered histone 14
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Synonyms gene
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Synonyms gene name
- H3 histone family, member M
- histone 2, H3c
- histone cluster 2, H3c
- histone cluster 2 H3 family member c
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-02-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 3
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Synonyms gene
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Synonyms gene name
- chromosome 17 open reading frame 33
- colony stimulating factor 3 (granulocyte)
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
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Tree numbers
- E01.370.225.500.386
- E05.196.712.516.600.240
- E05.200.500.386
- E05.242.386
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data