TBX1 Antibody, ALEXA FLUOR 555

• Catalog number
  bs-8257R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  TBX1 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-TBX1 PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TBX1
• Specificity
  This is a highly specific antibody against TBX1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TBX1
• Gene ID Number
  6899
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries.Involvement in disease:Haploinsufficiency of the TBX1 gene is responsible for most of the physical malformations present in DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS) . DGS is characterized by the association of several malformations: hypoplastic thymus and parathyroid glands, congenital conotruncal cardiopathy, and a subtle but characteristic facial dysmorphology. VCFS is marked by the association of congenital conotruncal heart defects, cleft palate or velar insufficiency, facial dysmorpholgy and learning difficulties. It is now accepted that these two syndromes represent two forms of clinical expression of the same entity manifesting at different stages of life.Defects in TBX1 are a cause of DiGeorge syndrome (DGS) .Defects in TBX1 are a cause of velocardiofacial syndrome (VCFS) .Defects in TBX1 are a cause of conotruncal heart malformations (CTHM). CTHM consist of cardiac outflow tract defects, such as tetralogy of Fallot, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis, and aortic arch anomalies.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  Brachyury; CAFS; CTHM; DGCR; DGS; DORV; T box 1; T box 1 transcription factor; T box 1 transcription factor C; T box; T box protein 1; T box transcription factor TBX 1; T box transcription factor TBX1; T-box 1; T-box protein 1; T-box transcription factor TBX1; TBX 1; TBX 1C; tbx1; TBX1_HUMAN; TBX1C; Testis specic T box protein; Testis-specic T-box protein; TGA; VCFS.
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  TBX1  
• Gene symbol
  TBX1
• Short name
  Anti-TBX1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  TBX1 Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies
• Alternative to gene target
  T-box 1, CAFS and CATCH22 and CTHM and DGCR and DGS and DORV and TBX1C and TGA and VCF and VCFS, TBX1 and IDBG-1419 and ENSG00000184058 and 6899, protein dimerization activity, nuclei, Tbx1 and IDBG-141945 and ENSMUSG00000009097 and 21380

Gene info

• Identity
  HGNC:11592
• Gene
  TBX1
• Long gene name
  T-box transcription factor 1
• Synonyms gene
  • VCF
• Synonyms gene name
  • velocardiofacial syndrome
  • T-box 1
• Synonyms
  • CATCH22
• GenBank acession
  • AF012131
• Locus
  22q11.21
• Discovery year
  1997-05-15
• Entrez gene record
  6899
• Pubmed identfication
  • 9268629
  • 23000736
• RefSeq identity
  • NM_080647
• Classification
  • T-box transcription factors
• VEGA ID
  OTTHUMG00000150421
• Locus Specific Databases
  • LRG_226

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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