MOUSE Anti-HUMAN C8 Antibody
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Catalog numberGEN212936
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PricePlease ask
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Size100ug
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Also known asC8
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Other namescomplement component C8 beta chain preproprotein; Complement component C8 beta chain; complement component C8 beta chain; complement component 8 subunit beta; complement component 8, beta polypeptide; Complement component 8 subunit beta
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameC8
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Gene name synonimsN/A
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Other gene namesC8B; C8B; N/A; N/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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Clone056B-373
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityC8 This item recognises complement component 8 (C8), a 151 kDa member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyses the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. _x000D__x000D_Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearancePurified (Purified IgG - liquid)
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ConcentrationIgG concentration 1.0mg/ml
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Storage and shippingStore the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
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Tested applicationsELISA (EIA), Immunohistology - Frozen (IHC), Flow Cytometry (FACS), Western Blot (WB)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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TestMBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target-
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Gene symbolHOXC8, C8G, AKR1C8
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Short nameMOUSE Anti- C8 Antibody
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Techniqueanti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, mouses
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Hostmouse
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SpeciesHuman, Humans, Mouses
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Alternative nameAnti-MOUSE ANTI HUMAN C8
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene namehomeobox C8
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Synonyms gene
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Synonyms gene name
- homeo box C8
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GenBank acession
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Locus
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Discovery year1990-06-15
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Entrez gene record
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Pubmed identfication
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Classification
- HOXL subclass homeoboxes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecomplement C8 gamma chain
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Synonyms gene name
- complement component 8, gamma polypeptide
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GenBank acession
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Locus
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Discovery year1988-05-11
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Entrez gene record
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Classification
- Lipocalins
- Complement system activation components
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namealdo-keto reductase family 1 member C8
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Synonyms gene
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Synonyms gene name
- aldo-keto reductase family 1, member C-like 1
- aldo-keto reductase family 1 member C8, pseudogene
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Locus
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Discovery year2004-05-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Aldo-keto reductases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
