StemBoost™ Neural Stem Cell Reprogramming Cocktail (100X)
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Catalog number
S238-1
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Price
Please ask
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Size
1 ml
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Description
StemBoost™ Neural Stem Cell Reprogramming Cocktail is a convenient, sterile-filtered cocktail solution (100X, in DMSO) containing eight (8) small molecules useful for reprogramming of fibroblasts into neural stem cells. The eight compounds are: CHIR99021 (Cat. No. 1677), LDN193189 (Cat. No. 1995), A83-01 (Cat. No. 1725), Tranylcypromine hemisulfate (Cat. No. 1816), RG 108 (Cat. No. 1679), Retinoic acid (Cat. No. 2218), SMER28 (Cat. No. 1856), and Hh Ag 1.5 (Cat. No. B2160).
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Structure Available
No
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Salt Form
No
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Cell Permeable
Yes
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Handling
Protect from air and light
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Tag Line
A neural stem cell reprogramming cocktail
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
36 months
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SMILES
N/A
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InChi
N/A
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InChi Key
N/A
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MSDS Available
Yes
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Additional description
For cells, cell lines and tissues in culture till half confluency.
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Test
Stem cell factors and stem cell growth factors will produce stem cells or be part of a transdifferentiation process to produce other cells. A cell can transdifferentiate by going back to the naive stem cell stadium or directly into the other cell, helped by the stem cell and transdifferentiationf actors. Stem cell growth factors or stem cell factors are mostly used to produce iPSCs or induced pluripotent stem cells by Jamaka or Thomson factors by using for example 5 Lenti-III-CMV viruses, expressing the Yamanaka iPSC factor set (Oct4, Sox2, Nanog and Lin28) + GFP positive control. Trans differentiation will omit the stem cell stadium but stem cell factors sill play an important role in trans differentiation strategies.
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