Histone H2A (1-129 aa), Xenopus recombinant
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Catalog number
7668-250
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Price
Please ask
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Size
250 ug
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Synonyms
Histone H2A (1-129 aa), Xenopus recombinant
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Alternative_names
H2A, H2a 615, H2A GL101, H2A histone family member A, H2A histone family member B
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Description
Core component of nucleosome
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Recombinant
Yes
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Source
E. coli
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Molecular Weight
13.9 kDa (1-129 aa)
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Storage Temp
-80°C
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Shipping
dry ice
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Shelf Life
6 months
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Appearance
Lyophilized powder
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Physical form description
Lyophilized powder. Recommended buffer is 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride, and 20% glycerol.
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Background Information
H2A is a core component of nucleosome. A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around an octamer of histones. The octamer is composed of two of each histone H2A, H2B, H3, and H4. DNA accessibility is regulated via a complex set of post-translational modifications of these histones, also called histone code, and nucleosome remodeling. Histones H2A and H2B form a dimer. Histones H3 and H4 form a tetramer. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core. Histone H3 undergoes many modifications which include acetylation, phosphorylation, ubiquitylation, sumoylation, and biotinylation that are important for regulation of gene transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
H2AC8, H2AC17, MIR129-1, H2AC20, H2AC7, H2AC18, H2AC11, H2AC19, H2AC15, MPC1
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Short name
Histone H2A (1-129 aa), Xenopus recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Xenopus, Xenopuses
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Alternative name
Histone H2A (1-129 aa), Xenopus Rec.
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 8
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Synonyms gene
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Synonyms gene name
- H2A histone family, member A
- histone 1, H2ae
- histone cluster 1, H2ae
- histone cluster 1 H2A family member e
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-08-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 17
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Synonyms gene
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Synonyms gene name
- H2A histone family, member N
- histone 1, H2am
- histone cluster 1, H2am
- histone cluster 1 H2A family member m
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
microRNA 129-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 20
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Synonyms gene
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Synonyms gene name
- H2A histone family, member Q
- histone 2, H2ac
- histone cluster 2, H2ac
- histone cluster 2 H2A family member c
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 7
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Synonyms gene
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Synonyms gene name
- H2A histone family, member G
- histone 1, H2ad
- histone cluster 1, H2ad
- histone cluster 1 H2A family member d
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-08-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 18
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Synonyms gene
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Synonyms gene name
- H2A histone family, member O
- histone 2, H2aa
- histone 2, H2aa3
- histone cluster 2, H2aa3
- histone cluster 2 H2A family member a3
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 11
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Synonyms gene
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Synonyms gene name
- H2A histone family, member P
- histone 1, H2ag
- histone cluster 1, H2ag
- histone cluster 1 H2A family member g
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-10-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 19
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Synonyms gene
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Synonyms gene name
- histone 2, H2aa4
- histone cluster 2, H2aa4
- histone cluster 2 H2A family member a4
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Synonyms
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GenBank acession
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Locus
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Discovery year
2006-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 15
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Synonyms gene
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Synonyms gene name
- H2A histone family, member D
- histone 1, H2ak
- histone cluster 1, H2ak
- histone cluster 1 H2A family member k
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Product files
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