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DICER1 - Blocking Peptide

DICER1 - Blocking Peptide is available 1 time from Nordc labs

X2771B | DICER1 - Blocking Peptide size: 50 μg | 185.32 USD

Catalog number X2771B
Supplier nordc
Price 185.32 USD
Size 50 μg
1. Gene info
Identity43017
Synonyms gene
Synonyms gene name
  • DICER1 antisense RNA (non-protein coding)
Synonyms
GenBank acession
Discovery year2011-09-16
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000150190
Category Proteins & Peptides
Antibody is raised in see techfile
Antibody's reacts with Blocking Peptide to Cat # X2756P
Antibody's suited for Antibody can be used for Immunohistochemistry (2-4 µg/ml) and Western blotting (1-2 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Protein number see ncbi
Antigen-antibody binding interaction DICER1 - Blocking Peptide
Clone not specified
Antibody come from Synthetic peptide derived from the human SALL4 protein
Other description Provided as solution in phosphate buffered saline with 0.08% sodium azide.
Long description This peptide is the immunogen used to make Cat # X2756P. _x000B__x000B_Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.
Antibody's reacts with these species This antibody doesn't cross react with other species
Storage -20ºC
Relevant references 1. Ma, Y., et al. ÔSALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice.Õ Blood, 108, 2726-2735 (2006)_x000B_2. Kohlhase, J., et al. ÔOkihiro syndrome is caused by SALL4 mutations.Õ Hum. Mol. Genet., 11, 2979-2987 (2002)_x000B_3. Yang, F., et al. ÔSumoylation is important for stability, subcellular localization, and transcriptional activity of SALL4, an essential stem cell transcription factor.Õ J. Biol. Chem., 287, 38600-38608 (2012)
Application Blocking Peptide
Warnings This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Antibody's specificity No Data Available
Test You can block the antibody by the specific target amino acid sequence of peptide.
Properties blocking peptide
Description Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
Gene targetDICER1
Short name DICER1 - Blocking Peptide
Technique blocking peptide, Blocking, peptide
Alternative name DICER1 - inhibiting short protein sequence
Alternative technique control
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