Anti-Mcl1 (Ser159 + Thr163), ALEXA Fluor 594
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Catalog numberGENTObs-3265R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideMcl1 Ser159 + Thr163
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SpecificityThese phosphorylation sites are homologous to Ser140 + Thr144 in Mouse and Ser139 + Thr143 in Rat.Mcl1 (Ser159 + Thr163)
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ModificationPhosphorylation
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Modification siteSer159 + Thr163
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsCytoplasm, Nucleus
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Antigen SourceKLH conjugated synthetic phosphopeptide derived from human Mcl 1 around the phosphorylation site of Ser159/Thr163
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Gene ID4170
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Swiss ProtQ07820
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationInvolved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsTM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; MCL1
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Also known asMcl1 (Ser159 + Thr163) Antibody
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Other nameAnti-Mcl1 (Ser159 + Thr163)
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Gene target
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Short nameAnti-Mcl1 (Ser159 + Thr163)
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Techniqueanti-, anti, antibody to, antibodies
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameMcl1 (Ser159 + Thr163) Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniqueantibodies
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Alternative to gene targetmyeloid cell leukemia sequence 1 (BCL2-related), bcl2-L-3 and BCL2L3 and EAT and Mcl-1 and MCL1-ES and mcl1/EAT and MCL1L and MCL1S and TM, MCL1 and IDBG-102145 and ENSG00000143384 and 4170, BH3 domain binding, nuclei, Mcl1 and IDBG-173221 and ENSMUSG00000038612 and 17210
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MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data