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Also known as
Epidermal Growth Factor Receptor (EGFR) (extracellular ligand binding site
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Other names
epidermal growth factor receptor; Epidermal growth factor receptor; epidermal growth factor receptor; OTTHUMP00000159661; OTTHUMP00000159662; OTTHUMP00000159663; OTTHUMP00000209210; OTTHUMP00000209211; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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Gene name synonims
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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Other gene names
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
EGF-R1
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Host organism
Mouse (Mus musculus) Source: Tissue Culture Supernatant
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Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Epidermal Growth Factor Receptor (EGFR) (extracellular ligand binding site Human EGF Receptor (extracellular ligand binding site). Does not cross react with v-erb-B.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Protein G chromatography
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Form Appearance
Purified, Lyophilized. Reconstitute with 10ul double distilled water.
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Concentration
1 miligram per 1 mililiter (prior to lyophilization)
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Storage and shipping
Store lyophilized product at 2 to 8 degree C. After reconstitution, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Avoid multiple freeze/thaw cycles.
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Tested applications
Block, EIA/ELISA, Flow Cytometry, Immunohistochemistry - Paraffin
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps