Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody

• Catalog number
  bs-3748R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody
• Also known as
  Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Acetyl and Histone H3(Ac-K10/p-Ser11)
• Specificity
  This is a highly specific antibody against Acetyl and Histone H3(Ac-K10/p-Ser11).
• Modification s
  Acetylation
• Modification site s
  Ac-K10/p-Ser11
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acetyl and Histone H3 (Ac-Lys10/p-Ser11)
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  H3 histone family member E pseudogene; H3F3; HIST3H3; Histone H3 3 pseudogene.
• Description
  N terminal acetylation or CH3CO as epigenetic regulation of Anti-Acetyl and Histone H3(Ac-K10/p-Ser11) by NATs.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Histone   Ac-K10/p-Ser11  
• Gene symbol
  KRT10
• Short name
  Anti-Acetyl and Histone H3(Ac-K10/p-Ser11)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6413
• Gene
  KRT10
• Long gene name
  keratin 10
• Synonyms gene
  • KPP
• Synonyms gene name
  • keratosis palmaris et plantaris
  • keratin 10, type I
• Synonyms
  • K10
  • CK10
• Synonyms name
  • cytokeratin 10
  • epidermolytic hyperkeratosis
• GenBank acession
  • J04029
• Locus
  17q21.2
• Discovery year
  1988-08-12
• Entrez gene record
  3858
• Pubmed identfication
  • 2461420
  • 16831889
• RefSeq identity
  • NM_000421
• Classification
  • Keratins, type I
• VEGA ID
  OTTHUMG00000133368

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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