LSD1 Polyclonal Antibody

• Catalog number
  MBS668163
• Price
  Please ask
• Size
  0.025 mg

• Products_type
  Antibody
• Products_short_name
  [LSD1]
• Other_names
  [lysine-specific histone demethylase 1A isoform a; Lysine-specific histone demethylase 1A; lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; amine oxidase (flavin containing) domain 2; flavin-containing amine oxidase domain-containing protein 2; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2]
• Products_gene_name
  [LSD1]
• Other_gene_names
  [KDM1A; KDM1A; AOF2; KDM1; LSD1; BHC110; AOF2; KDM1; KIAA0601; LSD1]
• Clonality
  Polyclonal
• Reactivity
  Human (Predicted Reactivity: Mouse, Rat
• Form
  Purified (Liquid)
• Concentration
  0.5mg/ml, 200µl
• Storage_stability
  Store antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles. Expire 1 year from date of purchase.
• Tested_application
  Western Blot (WB)
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  LSD1  
• Gene symbol
  KDM1A
• Short name
  LSD1 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit
• Alternative name
  LSD1 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:29079
• Gene
  KDM1A
• Long gene name
  lysine demethylase 1A
• Synonyms gene
  • AOF2
  • KDM1
• Synonyms gene name
  • amine oxidase (flavin containing) domain 2
  • lysine (K)-specific demethylase 1
• Synonyms
  • KIAA0601
  • BHC110
  • LSD1
• Synonyms name
  • Lysine-specific histone demethylase 1A
• GenBank acession
  • AL031428
• Locus
  1p36.12
• Discovery year
  2004-02-26
• Entrez gene record
  23028
• Pubmed identfication
  • 9628581
  • 12493763
• RefSeq identity
  • NM_015013
• Classification
  • MicroRNA protein coding host genes
  • Lysine demethylases
• VEGA ID
  OTTHUMG00000003220

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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