Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate

• Catalog number
  E918910
• Price
  Please ask
• Size
  250 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  In Stock
• Cas number
  161797-99-5
• Chemical s molecular weight
  263.31
• Chemical s main applications
  Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is used in the synthesis of the major metabolites of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
• Other name
  2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylic Acid Ethyl Ester; Ethyl 2-(4-Hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate
• Chemical s formula
  C13H13NO3S
• Physical properties
  Off-White Solid
• Melting temperature
  183-184ºC
• Boiling temperature
  No Data Available
• Chemical s soluble in
  DMSO (Slightly), Methanol (Very Slightly)
• Stability conditions
  No Data Available
• Storage
  Refrigerator
• Chemical s specifications

• Gene target
  Ethyl   4-Hydroxyphenyl   4-methylthiazole-5-carboxylate  
• Gene symbol
  MIR1302-5, PIRC22, PIRC23, PIRC20, PIRC21, HTR6, IGKV3OR2-5, IGHV2OR16-5, SNORD116-5, TGFB1I1
• Short name
  Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate
• Alternative name
  Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate

Gene info

• Identity
  HGNC:35297
• Gene
  MIR1302-5
• Long gene name
  microRNA 1302-5
• Synonyms gene
  • MIRN1302-5
• Synonyms
  • hsa-mir-1302-5
• Locus
  20q13.13
• Discovery year
  2008-11-03
• Entrez gene record
  100302146
• RefSeq identity
  • NR_031634
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37526
• Gene
  PIRC22
• Long gene name
  piwi-interacting RNA cluster 22
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313850
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37527
• Gene
  PIRC23
• Long gene name
  piwi-interacting RNA cluster 23
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313786
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37524
• Gene
  PIRC20
• Long gene name
  piwi-interacting RNA cluster 20
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313785
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37525
• Gene
  PIRC21
• Long gene name
  piwi-interacting RNA cluster 21
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313916
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:5301
• Gene
  HTR6
• Long gene name
  5-hydroxytryptamine receptor 6
• Synonyms gene name
  • 5-hydroxytryptamine (serotonin) receptor 6
  • 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
• Synonyms
  • 5-HT6
  • 5-HT6R
• GenBank acession
  • L41147
• Locus
  1p36.13
• Discovery year
  1997-12-11
• Entrez gene record
  3362
• Pubmed identfication
  • 8522988
• RefSeq identity
  • NM_000871
• Classification
  • 5-hydroxytryptamine receptors, G protein-coupled
• VEGA ID
  OTTHUMG00000002713

Gene info

• Identity
  HGNC:5832
• Gene
  IGKV3OR2-5
• Long gene name
  immunoglobulin kappa variable 3/OR2-5 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 3/OR2-5
  • immunoglobulin kappa variable 3/OR2-5 pseudogene
• Synonyms
  • IGKV3/OR2-5
• GenBank acession
  • X51882
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28854
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000184519

Gene info

• Identity
  HGNC:5579
• Gene
  IGHV2OR16-5
• Long gene name
  immunoglobulin heavy variable 2/OR16-5 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 2/OR16-5
• Synonyms
  • IGHV2/OR16-5
• GenBank acession
  • L25544
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  100129631
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000152881

Gene info

• Identity
  HGNC:33071
• Gene
  SNORD116-5
• Long gene name
  small nucleolar RNA, C/D box 116-5
• Synonyms
  • HBII-85-5
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033417
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003320
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:11767
• Gene
  TGFB1I1
• Long gene name
  transforming growth factor beta 1 induced transcript 1
• Synonyms
  • Hic-5
  • TSC-5
  • ARA55
  • HIC-5
• Synonyms name
  • hydrogen peroxide-inducible clone-5
• GenBank acession
  • AB007836
• Locus
  16p11.2
• Discovery year
  1998-03-23
• Entrez gene record
  7041
• Pubmed identfication
  • 9422762
  • 10075738
• Classification
  • LIM domain containing
• VEGA ID
  OTTHUMG00000132467

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