BAFF, human recombinant

• Catalog number
  4451-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, TNFSF13B, B-cell Activating Factor.
• Alternative_names
  BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, TNFSF13B, B-cell Activating Factor.
• Description
  A potent B cell activator
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Purity
  ≥95%
• Biological activity
  Determined by the dose-dependent stimulation of IL-8 production by human PBMC. The ED₅₀ for this effect is less than 10 ng/ml. Please note: results may vary with PBMC donors.
• Results
  10 ng/ml
• Molecular Weight
  19.335 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized from 0.3X PBS, pH 7.5
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
• Background Information
  Human BAFF (for B cell activating factor belonging to the TNF family) is a newly discovered novel ligand of the TNF family. BAFF plays an important role as co-stimulator of B cell proliferation and function. Recombinant human BAFF is a soluble 17.0 kDa protein containing 153 amino acid residues
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  BAFF  
• Gene symbol
  TNFSF13B
• Short name
  BAFF, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  BAFF, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:11929
• Gene
  TNFSF13B
• Long gene name
  TNF superfamily member 13b
• Synonyms gene
  • TNFSF20
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 13b
• Synonyms
  • BAFF
  • THANK
  • BLYS
  • TALL-1
  • TALL1
  • CD257
• Synonyms name
  • B-cell-activating factor
  • TNF and ApoL-related leukocyte expressed ligand 1
  • TNF homolog that activates apoptosis
  • B-lymphocyte stimulator
• GenBank acession
  • AF136293
• Locus
  13q33.3
• Discovery year
  1999-07-19
• Entrez gene record
  10673
• Pubmed identfication
  • 10331498
  • 10359578
• RefSeq identity
  • NM_006573
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000017329

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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