BAFF, human recombinant
-
Catalog number4451-1000
-
PricePlease ask
-
Size1 mg
-
-
SynonymsBAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, TNFSF13B, B-cell Activating Factor.
-
Alternative_namesBAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, TNFSF13B, B-cell Activating Factor.
-
DescriptionA potent B cell activator
-
RecombinantYes
-
SourceE. coli
-
Purity by SDS PAGE≥95%
-
AssaySDS-PAGE
-
Purity≥95%
-
Biological activityDetermined by the dose-dependent stimulation of IL-8 production by human PBMC. The ED₅₀ for this effect is less than 10 ng/ml. Please note: results may vary with PBMC donors.
-
Results10 ng/ml
-
Molecular Weight19.335 kDa
-
Storage Temp-20°C
-
ShippingGel pack
-
Shelf Life12 months
-
AppearanceLyophilized protein
-
Physical form descriptionLyophilized from 0.3X PBS, pH 7.5
-
Reconstitution InstructionsReconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
-
Background InformationHuman BAFF (for B cell activating factor belonging to the TNF family) is a newly discovered novel ligand of the TNF family. BAFF plays an important role as co-stimulator of B cell proliferation and function. Recombinant human BAFF is a soluble 17.0 kDa protein containing 153 amino acid residues
-
HandlingCentrifuge the vial prior to opening.
-
UsageFor Research Use Only! Not to be used in humans
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Additional sourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolTNFSF13B
-
Short nameBAFF, recombinant
-
TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
SpeciesHuman, Humans
-
Alternative nameBAFF, H. sapiens Rec.
-
Alternative techniquerec
-
Gene info
-
Identity
-
Gene
-
Long gene nameTNF superfamily member 13b
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 13b
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-07-19
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- CD molecules
- Tumor necrosis factor superfamily
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data