DR5 Antibody
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Catalog number3062-100
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PricePlease ask
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Size100 µg
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Antibody TargetDR5
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Target Alternative NameTNFRSF10B, TRICKB,TRANCE-R, ZTNFR9, CD262, TRICK2A, Apo2, TRAIL-R2, TRICK2, KILLER
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse
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Immunogen SequenceSynthetic peptide corresponding to residues surrounding amino acid 372 of mouse DR5 precursor
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AccessionQ9QZM4
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Gene Id21933
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AppearanceColorless liquid
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FormLiquid
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Concentration0.2 mg/ml
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Formulation100 µg (0.2 mg/ml) immunoaffinity purified rabbit anti-DR5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot
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Application And UsagesWestern blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects 60 kDa DR5 in samples of human and mouse origins
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DescriptionDR5 is the DD containing receptor for TRAIL, Apo2, TRAIL-R2, TRICK2, or KILLER. DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. Like DR3 and TNFR1, DR5 mediate apoptosis by FADD dependent pathway. Over-expression of DR5 induces apoptosis and activates NFkB.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTNFRSF10B
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Short nameDR5 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameDR5 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 10b
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 10b
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data